What Is Sonohysterography (SIS)?
Sonohysterography, also called a sonohysterogram or saline infusion sonography (SIS), is a minimally invasive ultrasound procedure used to evaluate the inside of the uterus. It involves filling the uterine cavity with sterile saline to provide a clearer, more detailed image of the endometrial lining and structure. This enhanced visualization helps identify abnormalities that may not be seen on a standard pelvic ultrasound.


When Is SIS Needed?
SIS is commonly recommended for:

  • Investigating abnormal uterine bleeding.
  • Diagnosing suspected uterine abnormalities, such as fibroids, polyps, or adhesions.
  • Evaluating causes of infertility or recurrent miscarriage.
  • Assessing the uterine cavity before fertility treatments like IVF or IUI.

Procedure Overview

  1. Preparation – Usually performed after menstruation but before ovulation.
  2. Catheter Placement – A thin catheter is gently inserted into the cervix.
  3. Saline Infusion – Sterile saline is introduced into the uterine cavity to expand it.
  4. Ultrasound Imaging – A transvaginal ultrasound is performed while the saline outlines the uterine walls, allowing the doctor to clearly see any abnormalities.
  5. Completion – The procedure takes about 15–30 minutes and does not require anesthesia.

Benefits

  • Provides a more detailed view of the uterine cavity than standard ultrasound.
  • Minimally invasive with minimal discomfort.
  • Can help guide treatment decisions for infertility and abnormal bleeding.
  • No radiation exposure.

Risks & Considerations

  • Mild cramping or spotting after the procedure.
  • Rare risk of infection.
  • Not performed if pregnancy is suspected or if there is a pelvic infection.